Happy birthday to me! Today is a day filled with celebration, reflection, and gratitude. It marks another year of growth, accomplishments, and the opportunity to create even more wonderful memories.














Happy birthday to me! Today is a day filled with celebration, reflection, and gratitude. It marks another year of growth, accomplishments, and the opportunity to create even more wonderful memories.
Abstract: Aim: The current SARS-CoV2 mutation occurs due to the opportunity provided by human animals for the replication of this pathogenic microbe. With the available data on the exponential spread of this pathogen, and the limited information on clinical manifestations severity, this systematic qualitative review (QSR) aimed to examine the exponential transmission of SARS-CoV2 omicron variant, disease severity, hospitalization and prognosis relative to previous variant mainly delta. Materials/Methods: This QSR was applied for literature review, implying study of studies in the assessment of evidence on transmission and disease severity associated with this novel variant, omicron, as well as recommended transmission mitigation measures. Results: The current data are indicative of the exponential spread of this variant due to several mutations relative to the delta variant as well as limited data on omicron disease severity, as well as clinical and public health measures in transmission mitigation and healthcare providers available in addressing acute, chronic and surgical conditions during this inter-season in the US.Conclusions: While the absence of evidence does not imply evidence of absence, this QRS clearly observed the exponential spread of the omicron variant globally, as well as limited data on clinical manifestations severity relative to the delta variant, as inconclusive. The omicron variant exponential spread is highly suggestive of implementing control and preventive measures in transmission mitigation and enhanced community herd immunity.
Introduction: Viral pathogens remain genetic materials and not living organisms, requiring host factors before replication and survival. The pathway to viral survival requires careful adaptability in the host, agent and environment interaction. Suppose the host in any viral infection is protected. In that case, exposure to such a
Materials & Methods: A systematic qualitative review (QSR) was used to examine non-peer-reviewed and scientific reports on omicron genomic sequencing, transmission dynamics, and severity of clinical features. This approach involved assessing the study and scientific report objectives, study or sample size, outcome/s, analysis, sub-population analysis and inference.
Results: While studying studies allows for evidence synthesis, all findings remain uncertain, implying sampling variability with random error quantification. The conclusions of this QRS observed the following:
(a) Omicron variant reflects an alternation in the genetic code of SARS-CoV2 delta variant, with the primary viral intent, is to enhance its survival in the host cell over time. These genetic codes serve as the source for the viral building, including the spike protein for SARS-CoV2. . The current geographic locale data reflects 2 to 3 times infection frequency, compared to two days retrospective infection frequency. Specifically, if the infection frequency of individuals in a specific setting within a geographic locale was (n=100) on Monday, on Wednesday, an estimated 300 were infected, indicative of exponential transmission of omicron. Omicron mutations had been observed to be more than 30, supporting this exponential transmission among vaccinated individuals. Typically, there is a doubling rate of the omicron variant every two to three days. However, increased mutations in any viral pathogen does not necessarily imply disease severity but viral survival.
(b) With several observed alterations in the SARS-CoV2 delta variant resulting in the omicron variant, the transmission rate is exponential due to these mutations in the Spike protein, which provides SARS-CoV2 with the opportunity to replicate in the host cell. The Omicron variant is highly transmissible due to the spike protein mutation and remains opportunistic in escaping the natural antibodies among individuals infected with the delta variant. Additionally, vaccinated individuals experience transmission due to antibodies limited cross-reactivity in inhibiting omicron replication - immune system escape.
(c) Omicron clinical manifestations with the current data reflect less severity than the delta variant. With more data on hospitalization, ICU admissions and mortality becoming available, more observations on the severity will emerge.
Conclusions and Recommendations: The global assessment of the SARS-CoV2 omicron variant is indicative of its exponential transmission relative to the delta variant; however reliable data are pending on comparable severity, hospitalization and mortality. Since all conclusions in scientific evidence discovery remain inconclusive, dynamic and not, static data application is required in clinical and public health decision making. This QSR recommends :
With the observed healthcare system incapacitation nationally and globally, if we as a human society fail to adhere to these viral disease control and preventive measures recommendations, including although not limited to fully vaccine uptake, sooner or later, the entire world as a human population will pre-transition to infectious disease as the leading cause of mortality. Realistically, based on this limited knowledge on SARS-CoV2 (COVID-19) pandemic, we as a scientific community must act now by informing the world community on a reliable and pragmatic approach to returning the human population to the pre-pandemic period.
A good CV increases your chances of landing your dream job.
As a recruiter, I receive a lot of CVs from people looking to fill job vacancies. In the last week, I have gone through more than 250 CVs.
So, when I hear job seekers complaining about sending several applications and not getting feedback, I know exactly what the problem is. They (job seekers) simply do not follow instructions. If you are job hunting, below are five tips to follow when sending your CV to a potential employer.
Just so you know, for every job opening, prospective employers receive an average of 200 to 250 applications. Recruiters in the private sector don’t have the luxury of going through volumes of unsolicited and often irrelevant papers. As a rule, if you have not been asked, do not send attachments of other documents with your CV. Your CV is enough!
Use an email address that has your official name. Companies have configured their Business Information System to reject and spam all mail from addresses with names that look like creatures from space. Often, those funny email handles and names are the reasons you never get shortlisted and hired.
You have never been employed but your CV is five pages, PDF and 5MB! Are you for real? Nobody wants to read about career goals, life objectives, profiles and other information which is mere grandstanding and political statements. For every application you make, review, revise and only send a CV that matches the requirements of the job. In HR practice, we look for a strategic fit between the candidate and the job. When you start your CV with things like religion, marital status, career objectives, you lose it even before it is read.
All recruiters suffer from something called criterion bias. This means if a candidate has structured his or her CV in a manner that shows the key education and professional qualifications and experiential knowledge that fit what they want, they will always be shortlisted. Do not give long winding stories that are not related to the role you are applying for.
Finally, Kenya has zero quality control in academic qualifications. Even a monkey with money can “acquire” a degree. So, when sending a CV, clearly indicate the name of the high school you attended and the grades you got.
“Energy usage trend over past few months is insane,” Musk tweeted.
Musk announced on Wednesday that Bitcoin would no longer be used to purchase Tesla vehicles because the company is “concerned about rapidly increasing use of fossil fuels for Bitcoin mining and transactions, especially coal, which has the worst emissions of any fuel.”
Musk has been one of the biggest proponents of Bitcoin, and his announcement caused it to fall by more than 10 percent, Reuters reported.
“Cryptocurrency is a good idea on many levels and we believe it has a promising future, but this cannot come at great cost to the environment,” Musk wrote on Wednesday.
The announcement to stop accepting Bitcoin for Tesla vehicles came only two months after Tesla began accepting the cryptocurrency for vehicle purchases.
Musk said that once Bitcoin can be produced with more sustainable energy, it
would accept it again.
“Tesla will not be selling any Bitcoin and we intend to use it for transactions as soon as mining transitions to more sustainable energy,” Musk said.